{"id":20317,"date":"2021-11-03T11:52:23","date_gmt":"2021-11-03T10:52:23","guid":{"rendered":"https:\/\/www.intimina.com\/blog\/?p=20317"},"modified":"2022-01-05T11:14:39","modified_gmt":"2022-01-05T10:14:39","slug":"pregnenolone-the-mother-hormone","status":"publish","type":"post","link":"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/","title":{"rendered":"Pregnenolone: The Mother Hormone"},"content":{"rendered":"\r\n<p>You\u2019ve been busy educating yourself on the complex world of reproductive health from <a href=\"https:\/\/www.intimina.com\/blog\/the-elusive-world-of-ovulation\/\">ovulation<\/a> to orgasms.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>You might have even taken a deep dive into the <a href=\"https:\/\/www.intimina.com\/blog\/hormones-understanding\/\">endocrine system<\/a> and the many roles that hormones play in your wellbeing.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>But there\u2019s one, very important, a hormone that\u2019s gone under the radar \u2013 until now.<\/p>\r\n\r\n\r\n\r\n<p>*Drumroll please*<\/p>\r\n\r\n\r\n\r\n<p>Presenting to you&#8230;<a href=\"https:\/\/www.usada.org\/spirit-of-sport\/education\/pregnenolone\/#:~:text=Pregnenolone%20is%20a%20hormone%20naturally,cortisol%2C%20estrogen%20and%20other%20hormones.\" target=\"_blank\" rel=\"noreferrer noopener nofollow\"> pregnenolone<\/a>!<\/p>\r\n\r\n\r\n\r\n<p>Try saying that five times fast.<\/p>\r\n\r\n\r\n\r\n<p>Let\u2019s learn all about this mysterious hormone.<\/p>\r\n\r\n\r\n\r\n<h2><strong>What is Pregnenolone?<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>You know pregnenolone is a hormone, but do you remember exactly what a hormone is?<\/p>\r\n\r\n\r\n\r\n<p>Hormones are essentially chemical messengers that tell different systems of your body what to do and when.<\/p>\r\n\r\n\r\n\r\n<p>So what makes pregnenolone special?<\/p>\r\n\r\n\r\n\r\n<p>Although it doesn\u2019t get enough credit, pregnenolone really runs the show.<\/p>\r\n\r\n\r\n\r\n<p>You\u2019ve heard of the big shots like cortisol, estrogen, testosterone, and progesterone, right? Well, none of those would be possible without pregnenolone.<\/p>\r\n\r\n\r\n\r\n<p>The body uses pregnenolone as the starting material for producing these well-known hormones, and many more.<\/p>\r\n\r\n\r\n\r\n<p>Hence the name \u201cthe mother hormone.\u201d It\u2019s also sometimes known as the \u201cprecursor\u201d or \u201cpro-hormone.\u201d<\/p>\r\n\r\n\r\n\r\n<h2><strong>How Does Pregnenolone Work?<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Pregnenolone is a steroid hormone that is made from cholesterol. Not only is it a steroid hormone, but it\u2019s also the first steroid hormone.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>This mother hormone is produced in the adrenal glands, as well as in the brain and gonads.<\/p>\r\n\r\n\r\n\r\n<p>Steroid hormones are essential for many everyday processes like your immune system, inflammation, metabolism, and sex characteristics.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>These are just a few of the hormones the pregnenolone helps to create:<\/p>\r\n\r\n\r\n\r\n<ul>\r\n<li>Estrogens<\/li>\r\n<li>Cortisol<\/li>\r\n<li>Progesterones<\/li>\r\n<li>Androgens (testosterone)<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p>Pregnenolone dictates what other hormones do and is the building block for much of your hormonal health.\u00a0<\/p>\r\n\r\n\r\n\r\n<h2><strong>Low Pregnenolone Levels<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Hormone levels naturally decline with age, the same is true for pregnenolone.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>Certain conditions may cause levels to dip at a younger age.<\/p>\r\n\r\n\r\n\r\n<p>Here are some signs that you may have low pregnenolone levels:<\/p>\r\n\r\n\r\n\r\n<ul>\r\n<li>Declining memory and mental awareness<\/li>\r\n<li>Fatigue and reduced mobility<\/li>\r\n<li>Join and muscle pain<\/li>\r\n<li>Dry skin<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p>If you think you may have low pregnenolone levels, you might be interested in pregnenolone supplementation.<\/p>\r\n\r\n\r\n\r\n<h2><strong>Pregnenolone Supplements<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Pregnenolone synthesis isn\u2019t limited to our bodies, it can also be created in a lab.<\/p>\r\n\r\n\r\n\r\n<p>Although there is limited evidence on the effects of pregnenolone therapy, it\u2019s been promoted as being able to help a myriad of conditions.<\/p>\r\n\r\n\r\n\r\n<h2><strong>Cognitive Health<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Supplementing pregnenolone may help with different aspects of cognitive health like memory and sleep.<\/p>\r\n\r\n\r\n\r\n<p>Because pregnenolone affects chemicals in the brain, it may play a role in psychiatric illnesses like <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4200497\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">bipolar disorder<\/a> and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3519851\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">schizophrenia<\/a>.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>In cases of schizophrenia, pregnenolone may improve some symptoms like a lack of emotion, limited speech, and the inability to feel pleasure.<\/p>\r\n\r\n\r\n\r\n<p>It may even help improve symptoms related to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4194260\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">autism<\/a>, like irritability and social functioning.\u00a0<\/p>\r\n\r\n\r\n\r\n<h2><strong>Chronic Pain<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Supplementing the hormone may affect inflammation and help with chronic pain.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>So far, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7052727\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">studies<\/a> have found that supplementing pregnenolone for four weeks had a significant impact on people with chronic low back pain.<\/p>\r\n\r\n\r\n\r\n<h2><strong>Anti Aging and Vitality<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Pregnenolone is often seen as an anti-ageing compound.<\/p>\r\n\r\n\r\n\r\n<p>The idea of supplementing it for this purpose is that it boosts the production of other hormones so that people feel younger and more energetic, with less fatigue.<\/p>\r\n\r\n\r\n\r\n<h2><strong>Chronic Conditions<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>The use of pregnenolone may help reduce the frequency of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7561372\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">seizures<\/a> in people with epilepsy.<\/p>\r\n\r\n\r\n\r\n<p>It may help improve symptoms of other conditions like <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26892094\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">multiple sclerosis<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30411422\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">endometriosis<\/a>, and certain skin conditions.<\/p>\r\n\r\n\r\n\r\n<p>In the United States, pregnenolone hormone replacements are not approved by the <a href=\"https:\/\/www.fda.gov\/food\/nutrition-education-resources-materials\/new-nutrition-facts-label?utm_source=Google&amp;utm_medium=search&amp;utm_campaign=newNFL2&amp;utm_content=runway-responsive\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Food and Drug Administration<\/a>.\u00a0<\/p>\r\n\r\n\r\n\r\n<h2><strong>Are There Any Side Effects of Pregnenolone Supplements?<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Because pregnenolone hormone therapy is not approved or regulated in most places, it\u2019s unclear what the potential side effects are.<\/p>\r\n\r\n\r\n\r\n<p>As of now, it\u2019s not recommended to take it for longer than twelve weeks.<\/p>\r\n\r\n\r\n\r\n<p>Some people have experienced side effects like:<\/p>\r\n\r\n\r\n\r\n<ul>\r\n<li>Irregular heartbeat<\/li>\r\n<li>Depressed mood<\/li>\r\n<li>Muscle pain<\/li>\r\n<li>A change in appetite<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p>Another precaution is if you have a medical condition that may be worsened by increased estrogen. Avoid taking pregnenolone supplements if you have uterine fibroids or reproductive cancers.<\/p>\r\n\r\n\r\n\r\n<p>Keep in mind that pregnenolone is a form of hormone therapy, not just a nutrition supplement, and it should be used with caution.<\/p>\r\n\r\n\r\n\r\n<h2><strong>What to Remember About Pregnenolone<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>Are you as amazed by the power of hormones as we are?\u00a0<\/p>\r\n\r\n\r\n\r\n<p>Who knew there was a widely unknown hormone that packs as powerful of a punch as pregnenolone?<\/p>\r\n\r\n\r\n\r\n<p>Now that you know a bit more about your hormonal system, you can better make the decisions you need to care for your health.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>Remember that pregnenolone is a hormone supplement and not one to be taken lightly. It\u2019s important to consult your healthcare practitioner before incorporating it into your routine.<\/p>\r\n\r\n\r\n\r\n<p>If you\u2019re wondering whether supplementing pregnenolone may help boost your health, give your doctor a call to discuss what your options are and to get your hormone levels tested.<\/p>\r\n\r\n\r\n\r\n<p>By testing your pregnenolone levels, your provider can help rule out conditions that may be affected by it, and get you feeling your best.<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve been busy educating yourself on the complex world of reproductive health from ovulation to orgasms.\u00a0 You might have even taken a deep dive into the endocrine system and the&hellip;<\/p>\n","protected":false},"author":24,"featured_media":20319,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[1],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.12 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Let\u2019s learn all about mysterious hormone called pregnenolone<\/title>\n<meta name=\"description\" content=\"If you\u2019re wondering whether supplementing pregnenolone may help boost your health, give your doctor a call to discuss what your options.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Natasha Weiss\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\"},\"author\":{\"name\":\"Natasha Weiss\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#\/schema\/person\/b6c60ecf47ec06a36c4b2f175253c5ff\"},\"headline\":\"Pregnenolone: The Mother Hormone\",\"datePublished\":\"2021-11-03T10:52:23+00:00\",\"dateModified\":\"2022-01-05T10:14:39+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\"},\"wordCount\":842,\"commentCount\":1,\"publisher\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/#organization\"},\"articleSection\":[\"Women's Health\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\",\"url\":\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\",\"name\":\"Let\u2019s learn all about mysterious hormone called pregnenolone\",\"isPartOf\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/#website\"},\"datePublished\":\"2021-11-03T10:52:23+00:00\",\"dateModified\":\"2022-01-05T10:14:39+00:00\",\"description\":\"If you\u2019re wondering whether supplementing pregnenolone may help boost your health, give your doctor a call to discuss what your options.\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.intimina.com\/blog\/pregnenolone-the-mother-hormone\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#website\",\"url\":\"https:\/\/www.intimina.com\/blog\/\",\"name\":\"Intimina\",\"description\":\"A Health and Wellness Resource for Women\",\"publisher\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.intimina.com\/blog\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#organization\",\"name\":\"Intimina\",\"url\":\"https:\/\/www.intimina.com\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.intimina.com\/blog\/wp-content\/uploads\/2019\/04\/INTIMINA_logo-02.png\",\"contentUrl\":\"https:\/\/www.intimina.com\/blog\/wp-content\/uploads\/2019\/04\/INTIMINA_logo-02.png\",\"width\":1000,\"height\":543,\"caption\":\"Intimina\"},\"image\":{\"@id\":\"https:\/\/www.intimina.com\/blog\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/intimina\",\"https:\/\/twitter.com\/intimina\",\"https:\/\/www.instagram.com\/intimina\/\",\"https:\/\/www.pinterest.com\/intimina\/\",\"https:\/\/www.youtube.com\/channel\/UCR_3_GPO6pkhDiFU9TZRdYA\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#\/schema\/person\/b6c60ecf47ec06a36c4b2f175253c5ff\",\"name\":\"Natasha Weiss\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.intimina.com\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/b65d7a92be626bc22ff8eb7ad41dbf0c?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/b65d7a92be626bc22ff8eb7ad41dbf0c?s=96&d=mm&r=g\",\"caption\":\"Natasha Weiss\"},\"description\":\"Natasha (she\/her) is a full-spectrum doula and health+wellness copywriter. 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